Why is praziquantel NOT effective against Fasciola hepatica?...

Question

Why is praziquantel NOT effective against Fasciola hepatica?

Accepted Answer

Fasciola tegument resists or rapidly repairs praziquantel-induced damage; triclabendazole is required instead

Answer

Fasciola lacks calcium channels

Answer

Praziquantel cannot reach bile ducts

Answer

Fasciola is not a trematode

Answer

Higher doses work

uk-dtmh MCQ (SBA): Praziquantel Inefficacy Against Fasciola