A child from Lake Victoria has hepatosplenomegaly from S. mansoni. After praziquantel, egg count falls to zero. Will portal hypertension resolve?...

Question

A child from Lake Victoria has hepatosplenomegaly from S. mansoni. After praziquantel, egg count falls to zero. Will portal hypertension resolve?

Accepted Answer

Praziquantel prevents new egg deposition but established periportal fibrosis is largely irreversible; portal hypertension may persist

Answer

Yes, praziquantel reverses all damage

Answer

Only surgical shunt helps

Answer

Higher praziquantel dose reverses fibrosis

Answer

Portal hypertension was unrelated

uk-dtmh MCQ (SBA): Irreversibility of Schistosomal Fibrosis