A 5-year-old child in Kenya presents with a painless, depigmented skin macule on his thigh with reduced sensation. A single peripheral nerve (left lat...

Question

A 5-year-old child in Kenya presents with a painless, depigmented skin macule on his thigh with reduced sensation. A single peripheral nerve (left lateral popliteal) is thickened. Slit-skin smear is negative. What is the WHO MDT regimen for single-lesion paucibacillary leprosy?

Accepted Answer

Single-dose ROM (rifampicin 600 mg + ofloxacin 400 mg + minocycline 100 mg) - although this regimen has been deprioritised by WHO in recent guidelines in favour of standard PB-MDT

Answer

Standard PB-MDT for 6 months

Answer

MB-MDT for 12 months

Answer

Dapsone monotherapy for 2 years

Answer

No treatment for single-lesion disease

uk-dtmh MCQ (SBA): Single-lesion PB Leprosy Treatment

A 5-year-old child in Kenya presents with a painless, depigmented skin macule on his thigh with reduced sensation. A single peripheral nerve (left lateral popliteal) is thickened. Slit-skin smear is negative. What is the WHO MDT regimen for single-lesion paucibacillary leprosy?