A 30-year-old HIV-positive woman from Zambia with a CD4 of 180 cells/µL asks about contraception while on DTG-based ART. She is interested in the comb...

Question

A 30-year-old HIV-positive woman from Zambia with a CD4 of 180 cells/µL asks about contraception while on DTG-based ART. She is interested in the combined oral contraceptive pill (COCP). Is there a clinically significant interaction between DTG and the COCP?

Accepted Answer

No clinically significant interaction; DTG does not significantly affect the efficacy of hormonal contraceptives, and hormonal contraceptives do not affect DTG levels

Answer

Yes; DTG completely inactivates the COCP

Answer

Only injectable depot medroxyprogesterone is safe with DTG

Answer

DTG is contraindicated with all hormonal contraception

Answer

Only barrier methods are safe

uk-dtmh MCQ (SBA): DTG and Contraception

A 30-year-old HIV-positive woman from Zambia with a CD4 of 180 cells/µL asks about contraception while on DTG-based ART. She is interested in the combined oral contraceptive pill (COCP). Is there a clinically significant interaction between DTG and the COCP?