A traveller asks about the typhoid conjugate vaccine (TCV). How does TCV differ from the older Vi polysaccharide vaccine?...

Question

A traveller asks about the typhoid conjugate vaccine (TCV). How does TCV differ from the older Vi polysaccharide vaccine?

Accepted Answer

TCV conjugates the Vi polysaccharide to a protein carrier, enabling T-cell dependent immune responses, immunological memory, and booster responses; it can be given from 6 months of age (unlike Vi polysaccharide which requires age ≥2 years)

Answer

TCV and Vi polysaccharide are identical

Answer

TCV is a live vaccine

Answer

TCV is given intranasally

Answer

TCV provides shorter protection than Vi polysaccharide

uk-dtmh MCQ (SBA): TCV vs Vi Polysaccharide Vaccine

A traveller asks about the typhoid conjugate vaccine (TCV). How does TCV differ from the older Vi polysaccharide vaccine?