A child in Pakistan develops extensively drug-resistant (XDR) typhoid fever. The isolate is resistant to chloramphenicol, ampicillin, co-trimoxazole, ...

Question

A child in Pakistan develops extensively drug-resistant (XDR) typhoid fever. The isolate is resistant to chloramphenicol, ampicillin, co-trimoxazole, fluoroquinolones, and third-generation cephalosporins. What treatment options remain?

Accepted Answer

Azithromycin (if the isolate is susceptible) and/or carbapenems (meropenem) for severe cases

Answer

No treatment exists

Answer

Oral metronidazole

Answer

IV vancomycin

Answer

Oral rifampicin

uk-dtmh MCQ (SBA): XDR Typhoid Treatment

A child in Pakistan develops extensively drug-resistant (XDR) typhoid fever. The isolate is resistant to chloramphenicol, ampicillin, co-trimoxazole, fluoroquinolones, and third-generation cephalosporins. What treatment options remain?