A 25-year-old man from central Tanzania presents with a febrile illness, chancre on the leg, and blood film showing trypanosomes. CSF shows 3 WBC/µL a...

Question

A 25-year-old man from central Tanzania presents with a febrile illness, chancre on the leg, and blood film showing trypanosomes. CSF shows 3 WBC/µL and no trypanosomes. He is diagnosed with stage 1 T. b. rhodesiense HAT. What is an important difference in treatment approach between rhodesiense and gambiense HAT?

Accepted Answer

For stage 1 rhodesiense, suramin is the treatment of choice; fexinidazole is NOT effective against T. b. rhodesiense

Answer

There is no difference in treatment

Answer

Fexinidazole can be used for both species

Answer

Pentamidine is used for both species in stage 1

Answer

Eflornithine works for both species

uk-dtmh MCQ (SBA): Rhodesiense vs Gambiense Treatment