A 32-year-old man presents with P. falciparum malaria (parasitaemia 2%) acquired in Burkina Faso. He has a known allergy to sulfonamides. He is prescr...

Question

A 32-year-old man presents with P. falciparum malaria (parasitaemia 2%) acquired in Burkina Faso. He has a known allergy to sulfonamides. He is prescribed artemether/lumefantrine. What is the relevance of his sulfonamide allergy to his antimalarial treatment?

Accepted Answer

Sulfonamide allergy is not relevant to artemether/lumefantrine; the drug does not contain sulfonamides and can be safely prescribed

Answer

Artemether/lumefantrine contains sulfonamides and is contraindicated

Answer

He must receive IV artesunate instead due to cross-reactivity

Answer

Atovaquone/proguanil is contraindicated because proguanil is a sulfonamide

Answer

All antimalarials are contraindicated in sulfonamide allergy

uk-dtmh MCQ (SBA): Sulfonamide Allergy and Antimalarials

A 32-year-old man presents with P. falciparum malaria (parasitaemia 2%) acquired in Burkina Faso. He has a known allergy to sulfonamides. He is prescribed artemether/lumefantrine. What is the relevance of his sulfonamide allergy to his antimalarial treatment?