A 30-year-old man from Angola is diagnosed with sleeping sickness (T. b. gambiense) with CNS involvement (stage 2, CSF WBC 25/µL). According to the la...

Question

A 30-year-old man from Angola is diagnosed with sleeping sickness (T. b. gambiense) with CNS involvement (stage 2, CSF WBC 25/µL). According to the latest WHO guidelines, which treatment is now recommended?

Accepted Answer

Fexinidazole for non-severe stage 2 (CSF WBC ≤20/µL); for severe stage 2 (CSF WBC >20/µL), NECT remains recommended

Answer

Melarsoprol

Answer

NECT (nifurtimox-eflornithine combination therapy)

Answer

Pentamidine

Answer

Suramin

uk-dtmh MCQ (SBA): Severe Stage 2 Gambiense HAT Treatment

A 30-year-old man from Angola is diagnosed with sleeping sickness (T. b. gambiense) with CNS involvement (stage 2, CSF WBC 25/µL). According to the latest WHO guidelines, which treatment is now recommended?