A 25-year-old pregnant woman from Sudan at 34 weeks' gestation develops hepatitis E infection. Her ALT is 3500 U/L and INR is 4.2. She is confused. Wh...

Question

A 25-year-old pregnant woman from Sudan at 34 weeks' gestation develops hepatitis E infection. Her ALT is 3500 U/L and INR is 4.2. She is confused. What is the most important prognostic concern?

Accepted Answer

She is at very high risk of fulminant hepatic failure and death - HEV genotype 1 in the third trimester carries a case fatality rate of 15-25%

Answer

HEV always resolves spontaneously in pregnancy

Answer

HEV only causes mild disease

Answer

Her baby will definitely have congenital HEV

Answer

Ribavirin should be started immediately

uk-dtmh MCQ (SBA): Fulminant HEV in Pregnancy

A 25-year-old pregnant woman from Sudan at 34 weeks' gestation develops hepatitis E infection. Her ALT is 3500 U/L and INR is 4.2. She is confused. What is the most important prognostic concern?