A 40-year-old man from Bihar presents with massive splenomegaly, pancytopaenia, and polyclonal hypergammaglobulinaemia. He is diagnosed with visceral ...

Question

A 40-year-old man from Bihar presents with massive splenomegaly, pancytopaenia, and polyclonal hypergammaglobulinaemia. He is diagnosed with visceral leishmaniasis. Which diagnostic test has the highest sensitivity but is also the most invasive?

Accepted Answer

Splenic aspirate microscopy (sensitivity >95%)

Answer

rK39 rapid test

Answer

Bone marrow aspirate microscopy

Answer

Lymph node aspirate microscopy

Answer

Peripheral blood buffy coat smear

uk-dtmh MCQ (SBA): VL Diagnostic Sensitivity Hierarchy

A 40-year-old man from Bihar presents with massive splenomegaly, pancytopaenia, and polyclonal hypergammaglobulinaemia. He is diagnosed with visceral leishmaniasis. Which diagnostic test has the highest sensitivity but is also the most invasive?