A 40-year-old man from the Democratic Republic of Congo presents with fever, hepatosplenomegaly, and pancytopaenia. He is HIV-positive with CD4 45 cel...

Question

A 40-year-old man from the Democratic Republic of Congo presents with fever, hepatosplenomegaly, and pancytopaenia. He is HIV-positive with CD4 45 cells/µL. Bone marrow biopsy shows small intracellular yeasts (2-4 µm) within macrophages on Giemsa stain. What is the most likely diagnosis?

Accepted Answer

Disseminated histoplasmosis caused by Histoplasma capsulatum

Answer

Visceral leishmaniasis

Answer

Talaromycosis

Answer

Disseminated tuberculosis

Answer

Cryptococcosis

uk-dtmh MCQ (SBA): Disseminated Histoplasmosis

A 40-year-old man from the Democratic Republic of Congo presents with fever, hepatosplenomegaly, and pancytopaenia. He is HIV-positive with CD4 45 cells/µL. Bone marrow biopsy shows small intracellular yeasts (2-4 µm) within macrophages on Giemsa stain. What is the most likely diagnosis?