A 28-year-old woman from rural Mozambique presents with a painless genital ulcer and bilateral inguinal lymphadenopathy. She is pregnant at 24 weeks. ...

Question

A 28-year-old woman from rural Mozambique presents with a painless genital ulcer and bilateral inguinal lymphadenopathy. She is pregnant at 24 weeks. RPR is reactive at 1:64 and TPHA is positive. What is the most appropriate treatment to prevent congenital syphilis?

Accepted Answer

Intramuscular benzathine penicillin G 2.4 million units single dose

Answer

Oral azithromycin 2 g single dose

Answer

Oral doxycycline 100 mg BD for 14 days

Answer

Intravenous ceftriaxone 1 g daily for 14 days

Answer

Oral erythromycin 500 mg QDS for 14 days

uk-dtmh MCQ (SBA): Syphilis in Pregnancy

A 28-year-old woman from rural Mozambique presents with a painless genital ulcer and bilateral inguinal lymphadenopathy. She is pregnant at 24 weeks. RPR is reactive at 1:64 and TPHA is positive. What is the most appropriate treatment to prevent congenital syphilis?