Placental malaria is a major cause of adverse pregnancy outcomes in P. falciparum endemic areas. Which parasite surface molecule mediates binding of p...

Question

Placental malaria is a major cause of adverse pregnancy outcomes in P. falciparum endemic areas. Which parasite surface molecule mediates binding of parasitised erythrocytes to chondroitin sulphate A (CSA) in the placental intervillous space?

Accepted Answer

VAR2CSA, a variant of PfEMP1

Answer

Circumsporozoite protein (CSP)

Answer

Merozoite surface protein 1 (MSP-1)

Answer

Histidine-rich protein 2 (HRP2)

Answer

Knob-associated histidine-rich protein (KAHRP)

uk-dtmh MCQ (SBA): Placental Malaria Molecular Basis

Placental malaria is a major cause of adverse pregnancy outcomes in P. falciparum endemic areas. Which parasite surface molecule mediates binding of parasitised erythrocytes to chondroitin sulphate A (CSA) in the placental intervillous space?