A 60-year-old man with well-controlled hypertension on amlodipine develops P. vivax malaria after travel to India. He is treated with chloroquine. Whi...

Question

A 60-year-old man with well-controlled hypertension on amlodipine develops P. vivax malaria after travel to India. He is treated with chloroquine. Which potential drug interaction should be considered when prescribing primaquine for radical cure?

Accepted Answer

No clinically significant interaction exists between primaquine and amlodipine

Answer

Primaquine interacts with amlodipine causing severe hypotension

Answer

Primaquine is contraindicated with all antihypertensives

Answer

Chloroquine and amlodipine interact causing fatal arrhythmia

Answer

Primaquine causes hypertensive crisis with calcium channel blockers

uk-dtmh MCQ (SBA): Primaquine Drug Interactions

A 60-year-old man with well-controlled hypertension on amlodipine develops P. vivax malaria after travel to India. He is treated with chloroquine. Which potential drug interaction should be considered when prescribing primaquine for radical cure?