A 30-year-old man on standard first-line anti-TB treatment develops painful, swollen joints (particularly the great toe) and elevated serum uric acid ...

Question

A 30-year-old man on standard first-line anti-TB treatment develops painful, swollen joints (particularly the great toe) and elevated serum uric acid (680 µmol/L). Which drug is most likely responsible?

Accepted Answer

Pyrazinamide

Answer

Rifampicin

Answer

Isoniazid

Answer

Ethambutol

Answer

Streptomycin

uk-dtmh MCQ (SBA): Pyrazinamide-induced Hyperuricaemia

A 30-year-old man on standard first-line anti-TB treatment develops painful, swollen joints (particularly the great toe) and elevated serum uric acid (680 µmol/L). Which drug is most likely responsible?