A patient on standard TB treatment develops orange-red discolouration of urine, tears, and sweat. Which drug is responsible, and is this clinically si...

Question

A patient on standard TB treatment develops orange-red discolouration of urine, tears, and sweat. Which drug is responsible, and is this clinically significant?

Accepted Answer

Rifampicin; this is a harmless and expected side effect that does not require treatment modification

Answer

Isoniazid; this indicates hepatotoxicity and treatment should be stopped

Answer

Pyrazinamide; this indicates hyperuricaemia

Answer

Ethambutol; this indicates renal impairment

Answer

Streptomycin; this indicates ototoxicity

uk-dtmh MCQ (SBA): Rifampicin Side Effects

A patient on standard TB treatment develops orange-red discolouration of urine, tears, and sweat. Which drug is responsible, and is this clinically significant?