A 55-year-old man presents with a right iliac fossa mass. Colonoscopy reveals a flask-shaped ulcer with undermined edges in the caecum. Biopsy shows t...

Question

A 55-year-old man presents with a right iliac fossa mass. Colonoscopy reveals a flask-shaped ulcer with undermined edges in the caecum. Biopsy shows trophozoites with ingested erythrocytes. What is the characteristic histological appearance of amoebic colitis?

Accepted Answer

Flask-shaped ulcers extending through the mucosa into the submucosa with relatively intact surrounding mucosa

Answer

Caseating granulomata

Answer

Diffuse crypt abscesses with goblet cell depletion

Answer

Non-caseating granulomata throughout the bowel wall

Answer

Pseudomembranes overlying necrotic mucosa

uk-dtmh MCQ (SBA): Amoebic Colitis Histology

A 55-year-old man presents with a right iliac fossa mass. Colonoscopy reveals a flask-shaped ulcer with undermined edges in the caecum. Biopsy shows trophozoites with ingested erythrocytes. What is the characteristic histological appearance of amoebic colitis?