In P. falciparum malaria, what is the role of PfEMP1 (P. falciparum erythrocyte membrane protein 1) in disease pathogenesis?...

Question

In P. falciparum malaria, what is the role of PfEMP1 (P. falciparum erythrocyte membrane protein 1) in disease pathogenesis?

Accepted Answer

PfEMP1 mediates cytoadherence of parasitised red cells to endothelial receptors, causing microvascular sequestration

Answer

PfEMP1 is the target of the RTS,S vaccine

Answer

PfEMP1 is a secreted toxin that directly causes cerebral oedema

Answer

PfEMP1 inhibits the host immune response by destroying antibodies

Answer

PfEMP1 is the antigen detected by rapid diagnostic tests

uk-dtmh MCQ (SBA): PfEMP1 and Cytoadherence