An HIV-positive patient with a CD4 count of 35 cells/µL develops progressive multifocal leukoencephalopathy (PML). MRI shows asymmetric, non-enhancing...

Question

An HIV-positive patient with a CD4 count of 35 cells/µL develops progressive multifocal leukoencephalopathy (PML). MRI shows asymmetric, non-enhancing white matter lesions. What is the causative agent and the mainstay of treatment?

Accepted Answer

JC virus; antiretroviral therapy to restore immune function

Answer

CMV; ganciclovir

Answer

Toxoplasma gondii; sulfadiazine and pyrimethamine

Answer

Cryptococcus neoformans; amphotericin B

Answer

EBV; rituximab

uk-dtmh MCQ (SBA): Progressive Multifocal Leukoencephalopathy

An HIV-positive patient with a CD4 count of 35 cells/µL develops progressive multifocal leukoencephalopathy (PML). MRI shows asymmetric, non-enhancing white matter lesions. What is the causative agent and the mainstay of treatment?