A 28-year-old woman from Uganda presents with a 2-week history of progressive somnolence, personality change, and tremor. She was diagnosed with Human...

Question

A 28-year-old woman from Uganda presents with a 2-week history of progressive somnolence, personality change, and tremor. She was diagnosed with Human African Trypanosomiasis (T. b. rhodesiense) 1 week ago and started on treatment. Her current symptoms suggest CNS involvement (stage 2 disease). CSF examination shows >5 WBC/µL and trypanosomes on CSF wet preparation. What is the most appropriate treatment for stage 2 East African trypanosomiasis?

Accepted Answer

Melarsoprol

Answer

Pentamidine

Answer

Suramin

Answer

Eflornithine

Answer

Fexinidazole

uk-dtmh MCQ (SBA): Stage 2 East African Trypanosomiasis