During IV artesunate treatment for severe malaria, a patient develops blackwater fever with passage of dark red-brown urine. Urinalysis shows haemoglo...

Question

During IV artesunate treatment for severe malaria, a patient develops blackwater fever with passage of dark red-brown urine. Urinalysis shows haemoglobinuria. What is the most likely underlying mechanism?

Accepted Answer

Massive intravascular haemolysis with haemoglobinuria

Answer

Direct nephrotoxicity from artesunate

Answer

Rhabdomyolysis from prolonged immobility

Answer

Haemorrhagic cystitis from quinine

Answer

Urinary tract infection with haematuria

uk-dtmh MCQ (SBA): Blackwater Fever

During IV artesunate treatment for severe malaria, a patient develops blackwater fever with passage of dark red-brown urine. Urinalysis shows haemoglobinuria. What is the most likely underlying mechanism?