An HIV-positive patient with a CD4 count of 60 cells/µL and a positive serum cryptococcal antigen (CrAg) has no symptoms of meningitis and a normal lu...

Question

An HIV-positive patient with a CD4 count of 60 cells/µL and a positive serum cryptococcal antigen (CrAg) has no symptoms of meningitis and a normal lumbar puncture. What is the recommended management?

Accepted Answer

Fluconazole 800 mg daily for 2 weeks then 400 mg daily for 8 weeks as pre-emptive therapy

Answer

No treatment; monitor clinically

Answer

Full induction therapy with amphotericin B and flucytosine

Answer

Itraconazole 200 mg daily

Answer

Start ART immediately without antifungal treatment

uk-dtmh MCQ (SBA): Cryptococcal Antigen Screen-and-Treat

An HIV-positive patient with a CD4 count of 60 cells/µL and a positive serum cryptococcal antigen (CrAg) has no symptoms of meningitis and a normal lumbar puncture. What is the recommended management?