A 30-year-old woman at 14 weeks of gestation attends the GP. She has a history of a previous pregnancy affected by alloimmune anti-D antibodies (Rh di...

Question

A 30-year-old woman at 14 weeks of gestation attends the GP. She has a history of a previous pregnancy affected by alloimmune anti-D antibodies (Rh disease) requiring intrauterine transfusion. She is Rh D negative. Her current antibody screen shows anti-D at a titre of 1:32. Which is the single most appropriate management?

Accepted Answer

Urgent referral to a fetal medicine unit for serial monitoring of the fetus for anaemia, including middle cerebral artery Doppler assessment

Answer

Routine antenatal care - anti-D antibodies are expected and not concerning

Answer

Administer anti-D immunoglobulin to suppress the antibodies

Answer

Arrange elective delivery at 28 weeks

Answer

Repeat the antibody screen at 36 weeks

uk-drcog MCQ (SBA): Rh Alloimmunisation - Fetal Medicine Referral