A 44-year-old woman with a BMI of 40 kg/m², type 2 diabetes, and nulliparity asks the GP about her risk of endometrial cancer. She has irregular perio...

Question

A 44-year-old woman with a BMI of 40 kg/m², type 2 diabetes, and nulliparity asks the GP about her risk of endometrial cancer. She has irregular periods (every 2-6 months) and has never used hormonal contraception. Which combination of risk factors makes her particularly high-risk?

Accepted Answer

Obesity, anovulation (with prolonged unopposed oestrogen), diabetes, and nulliparity are all independent risk factors for endometrial cancer - their combination significantly increases her risk

Answer

Obesity alone

Answer

Only nulliparity is a risk factor

Answer

Diabetes is protective against endometrial cancer

Answer

Irregular periods reduce endometrial cancer risk

uk-drcog MCQ (SBA): Combined Endometrial Cancer Risk Factors

A 44-year-old woman with a BMI of 40 kg/m², type 2 diabetes, and nulliparity asks the GP about her risk of endometrial cancer. She has irregular periods (every 2-6 months) and has never used hormonal contraception. Which combination of risk factors makes her particularly high-risk?