A 50-year-old woman starting HRT asks the GP about the type of progestogen. She has read that micronised progesterone (Utrogestan) is safer than synth...

Question

A 50-year-old woman starting HRT asks the GP about the type of progestogen. She has read that micronised progesterone (Utrogestan) is safer than synthetic progestogens. Which is the most accurate advice?

Accepted Answer

Micronised progesterone may be associated with a lower breast cancer risk and lower VTE risk compared to synthetic progestogens such as norethisterone and medroxyprogesterone acetate, though evidence is largely observational

Answer

All progestogens carry the same risk profile

Answer

Micronised progesterone is not available on the NHS

Answer

Synthetic progestogens are safer than micronised progesterone

Answer

Progestogen choice makes no difference to side effects

uk-drcog MCQ (SBA): Micronised Progesterone vs Synthetic Progestogens

A 50-year-old woman starting HRT asks the GP about the type of progestogen. She has read that micronised progesterone (Utrogestan) is safer than synthetic progestogens. Which is the most accurate advice?