A 36-year-old woman with severe PMS that has not responded to lifestyle changes, CBT, or vitamin B6 attends the GP. Her symptoms are primarily mood-re...

Question

A 36-year-old woman with severe PMS that has not responded to lifestyle changes, CBT, or vitamin B6 attends the GP. Her symptoms are primarily mood-related (severe irritability and depression in the luteal phase). Which pharmacological treatment has the strongest evidence for PMS mood symptoms?

Accepted Answer

Selective serotonin reuptake inhibitor (SSRI) - either continuously or in the luteal phase only

Answer

Combined oral contraceptive pill

Answer

Diazepam 5 mg PRN

Answer

Lithium

Answer

Progesterone pessaries

uk-drcog MCQ (SBA): SSRI for PMS Mood Symptoms

A 36-year-old woman with severe PMS that has not responded to lifestyle changes, CBT, or vitamin B6 attends the GP. Her symptoms are primarily mood-related (severe irritability and depression in the luteal phase). Which pharmacological treatment has the strongest evidence for PMS mood symptoms?