A 33-year-old woman at 10 weeks of gestation attends the GP for booking. She is a known hepatitis B carrier (HBsAg positive, HBeAg positive) with a hi...

Question

A 33-year-old woman at 10 weeks of gestation attends the GP for booking. She is a known hepatitis B carrier (HBsAg positive, HBeAg positive) with a high viral load (>10⁷ IU/mL). She is under hepatology follow-up. In addition to ensuring the neonate receives hepatitis B vaccine and HBIG at birth, which additional intervention is recommended?

Accepted Answer

Antiviral therapy (tenofovir) from 28-32 weeks to reduce viral load and further reduce vertical transmission risk

Answer

No additional intervention beyond neonatal immunoprophylaxis

Answer

Elective caesarean section for all HBeAg positive women

Answer

Separation of mother and baby at birth

Answer

Avoidance of breastfeeding

uk-drcog MCQ (SBA): High Viral Load HBV - Tenofovir in Pregnancy