A 31-year-old woman with rheumatoid arthritis attends the GP at 6 weeks of gestation. She is currently taking methotrexate 15 mg weekly, folic acid 5 ...

Question

A 31-year-old woman with rheumatoid arthritis attends the GP at 6 weeks of gestation. She is currently taking methotrexate 15 mg weekly, folic acid 5 mg weekly (not on methotrexate day), and naproxen 500 mg twice daily. Which is the single most appropriate prescribing change?

Accepted Answer

Stop methotrexate immediately and refer urgently to rheumatology

Answer

Continue methotrexate at a reduced dose of 7.5 mg weekly

Answer

Continue all current medications as the benefits outweigh the risks

Answer

Stop methotrexate and naproxen and commence prednisolone

Answer

Stop methotrexate only and continue naproxen throughout pregnancy

uk-drcog MCQ (SBA): Methotrexate in Pregnancy

A 31-year-old woman with rheumatoid arthritis attends the GP at 6 weeks of gestation. She is currently taking methotrexate 15 mg weekly, folic acid 5 mg weekly (not on methotrexate day), and naproxen 500 mg twice daily. Which is the single most appropriate prescribing change?