A 25-year-old woman at 10 weeks of gestation has routine booking bloods which reveal a positive syphilis serology (reactive Treponema pallidum EIA and...

Question

A 25-year-old woman at 10 weeks of gestation has routine booking bloods which reveal a positive syphilis serology (reactive Treponema pallidum EIA and positive TPPA). She has no symptoms and no history of previous syphilis treatment. Which is the single most appropriate management?

Accepted Answer

Refer urgently to genitourinary medicine for treatment with intramuscular benzathine benzylpenicillin

Answer

Repeat serology in 4 weeks to confirm and then treat

Answer

Prescribe oral doxycycline 100 mg twice daily for 14 days

Answer

Defer treatment until after delivery to avoid fetal complications

Answer

Prescribe oral amoxicillin 500 mg three times daily for 14 days

uk-drcog MCQ (SBA): Syphilis in Pregnancy

A 25-year-old woman at 10 weeks of gestation has routine booking bloods which reveal a positive syphilis serology (reactive Treponema pallidum EIA and positive TPPA). She has no symptoms and no history of previous syphilis treatment. Which is the single most appropriate management?