A woman with epilepsy on perampanel 8 mg daily asks whether this dose of perampanel is an enzyme inducer. What should she be told?...

Question

A woman with epilepsy on perampanel 8 mg daily asks whether this dose of perampanel is an enzyme inducer. What should she be told?

Accepted Answer

Perampanel is considered an enzyme inducer by FSRH. While evidence suggests the enzyme-inducing effect may be more significant at doses ≥12 mg/day, FSRH lists perampanel at any dose as a potential concern. She should use a method unaffected by enzyme inducers

Answer

Perampanel is an enzyme inducer at all doses

Answer

Perampanel is not an enzyme inducer at any dose

Answer

Only doses above 24 mg interact with contraception

Answer

Perampanel only interacts with the POP

uk-dfsrh MCQ (SBA): Perampanel Any Dose FSRH Cautious Enzyme Inducer

A woman with epilepsy on perampanel 8 mg daily asks whether this dose of perampanel is an enzyme inducer. What should she be told?