A 26-year-old woman with a known penicillin allergy (anaphylaxis) is diagnosed with early syphilis. Benzathine penicillin cannot be given. What is the...

Question

A 26-year-old woman with a known penicillin allergy (anaphylaxis) is diagnosed with early syphilis. Benzathine penicillin cannot be given. What is the recommended alternative treatment?

Accepted Answer

Doxycycline 100 mg twice daily for 14 days

Answer

Azithromycin 2 g stat

Answer

Ceftriaxone 1 g IM for 10 days - if no cephalosporin cross-reactivity

Answer

Erythromycin 500 mg QDS for 14 days

Answer

Amoxicillin 500 mg TDS for 14 days

uk-dfsrh MCQ (SBA): Syphilis Treatment Penicillin Anaphylaxis Alternative

A 26-year-old woman with a known penicillin allergy (anaphylaxis) is diagnosed with early syphilis. Benzathine penicillin cannot be given. What is the recommended alternative treatment?