A 28-year-old woman with latent tuberculosis is started on rifampicin and isoniazid. She uses a desogestrel POP. What contraceptive advice is needed?...

Question

A 28-year-old woman with latent tuberculosis is started on rifampicin and isoniazid. She uses a desogestrel POP. What contraceptive advice is needed?

Accepted Answer

Rifampicin is a potent enzyme inducer; the POP efficacy is reduced. She should switch to Cu-IUD, LNG-IUS, or DMPA

Answer

No change; isoniazid and rifampicin are not enzyme inducers

Answer

Isoniazid is the enzyme inducer, not rifampicin

Answer

She should double her POP dose

Answer

She should take the POP 6 hours before rifampicin

uk-dfsrh MCQ (SBA): Rifampicin TB Treatment POP Interaction