A 28-year-old woman with a BMI of 26 kg/m² has just started perampanel for epilepsy. She uses a desogestrel POP. What contraceptive advice is needed?...

Question

A 28-year-old woman with a BMI of 26 kg/m² has just started perampanel for epilepsy. She uses a desogestrel POP. What contraceptive advice is needed?

Accepted Answer

Perampanel is classified as an enzyme inducer by FSRH; at doses ≥12 mg/day the interaction is significant. She should consider switching to a method unaffected by enzyme inducers

Answer

No change is needed; perampanel is not an enzyme inducer

Answer

Perampanel only interacts with CHC

Answer

She should double her POP dose

Answer

Perampanel is safe with all contraception at any dose

uk-dfsrh MCQ (SBA): Perampanel Enzyme Inducer POP Interaction

A 28-year-old woman with a BMI of 26 kg/m² has just started perampanel for epilepsy. She uses a desogestrel POP. What contraceptive advice is needed?