A woman on long-term CHC asks about the effect of oestrogen on thyroxine-binding globulin (TBG). What is the interaction?...

Question

A woman on long-term CHC asks about the effect of oestrogen on thyroxine-binding globulin (TBG). What is the interaction?

Accepted Answer

Oestrogen increases TBG, which may increase the binding of thyroid hormones and necessitate a dose increase of levothyroxine in hypothyroid women

Answer

Oestrogen decreases TBG

Answer

Oestrogen has no effect on TBG

Answer

Oestrogen directly inhibits thyroid function

Answer

Only progestogens affect TBG

uk-dfsrh MCQ (SBA): Oestrogen Increases TBG Mechanism