A woman using a combined oral contraceptive pill (COC) is also prescribed fluconazole for vaginal candidiasis. What effect does fluconazole have on th...

Question

A woman using a combined oral contraceptive pill (COC) is also prescribed fluconazole for vaginal candidiasis. What effect does fluconazole have on the COC?

Accepted Answer

Fluconazole may increase ethinylestradiol levels as it is an enzyme inhibitor

Answer

Fluconazole reduces COC effectiveness by enzyme induction

Answer

Fluconazole has no pharmacokinetic interaction with the COC

Answer

Fluconazole causes the COC to be completely ineffective

Answer

Fluconazole should not be co-prescribed with any hormonal contraception

uk-dfsrh MCQ (SBA): Fluconazole Enzyme Inhibition and COC

A woman using a combined oral contraceptive pill (COC) is also prescribed fluconazole for vaginal candidiasis. What effect does fluconazole have on the COC?