A 35-year-old woman with well-controlled epilepsy on lamotrigine monotherapy asks about contraception. Why should she be cautioned about using CHC?...

Question

A 35-year-old woman with well-controlled epilepsy on lamotrigine monotherapy asks about contraception. Why should she be cautioned about using CHC?

Accepted Answer

CHC increases hepatic metabolism of lamotrigine, potentially reducing seizure control

Answer

Lamotrigine is an enzyme inducer that reduces CHC efficacy

Answer

CHC is UKMEC 4 with any antiepileptic drug

Answer

Lamotrigine causes CHC to have an increased risk of VTE

Answer

There is no interaction between lamotrigine and CHC

uk-dfsrh MCQ (SBA): Lamotrigine and CHC Interaction