A 50-year-old female develops complete heart block with a ventricular escape rate of 28 bpm after taking an accidental overdose of her verapamil table...

Question

A 50-year-old female develops complete heart block with a ventricular escape rate of 28 bpm after taking an accidental overdose of her verapamil tablets. She is hypotensive (65/35 mmHg) and drowsy. Atropine 3 mg IV has been ineffective. What is the specific antidote for calcium channel blocker toxicity?

Accepted Answer

IV calcium chloride 10% - 10-20 mL repeated as needed; also consider high-dose insulin euglycaemic therapy (HIET)

Answer

IV naloxone 400 micrograms

Answer

IV sodium bicarbonate 8.4%

Answer

IV glucagon 5 mg - the specific antidote for all cardiovascular drug overdoses

Answer

IV flumazenil 200 micrograms

uk-dipimc MCQ (SBA): CCB Overdose - Calcium Chloride