A pre-hospital team is managing a patient who has ingested an unknown quantity of tricyclic antidepressants (amitriptyline). His ECG shows a QRS durat...

Question

A pre-hospital team is managing a patient who has ingested an unknown quantity of tricyclic antidepressants (amitriptyline). His ECG shows a QRS duration of 160 ms (prolonged) and he is becoming increasingly drowsy. What is the specific pharmacological treatment for TCA cardiotoxicity?

Accepted Answer

Sodium bicarbonate 8.4% - 50 mL (50 mmol) IV bolus

Answer

Intralipid 20% - IV bolus and infusion

Answer

Calcium chloride 10% - 10 mL IV

Answer

Flumazenil 200 micrograms IV

Answer

Magnesium sulphate 2 g IV

uk-dipimc MCQ (SBA): TCA Overdose

A pre-hospital team is managing a patient who has ingested an unknown quantity of tricyclic antidepressants (amitriptyline). His ECG shows a QRS duration of 160 ms (prolonged) and he is becoming increasingly drowsy. What is the specific pharmacological treatment for TCA cardiotoxicity?