You are called to a nightclub where a 22-year-old male has collapsed. His friends say he took 'MDMA'. He is having a generalised seizure, is hyperther...

Question

You are called to a nightclub where a 22-year-old male has collapsed. His friends say he took 'MDMA'. He is having a generalised seizure, is hyperthermic at 41°C, and has a rigid jaw. His GCS post-ictally is 5. What is the most dangerous complication to anticipate?

Accepted Answer

All of the above - MDMA toxicity can cause a fulminant syndrome with DIC, rhabdomyolysis, multi-organ failure, and hyperthermia

Answer

Serotonin syndrome progressing to multi-organ failure

Answer

Isolated dehydration requiring IV fluids only

Answer

Rhabdomyolysis leading to acute kidney injury

Answer

Disseminated intravascular coagulation (DIC) secondary to hyperthermia

uk-dipimc MCQ (SBA): MDMA Toxicity

You are called to a nightclub where a 22-year-old male has collapsed. His friends say he took 'MDMA'. He is having a generalised seizure, is hyperthermic at 41°C, and has a rigid jaw. His GCS post-ictally is 5. What is the most dangerous complication to anticipate?