A 72-year-old female with known atrial fibrillation on apixaban 5 mg BD presents with sudden-onset right-sided hemiplegia and global aphasia. Symptom ...

Question

A 72-year-old female with known atrial fibrillation on apixaban 5 mg BD presents with sudden-onset right-sided hemiplegia and global aphasia. Symptom onset was 90 minutes ago. Her blood glucose is 5.8 mmol/L. What is the significance of her apixaban use in the context of acute stroke management?

Accepted Answer

Apixaban use means thrombolysis is generally contraindicated unless specific reversal or drug level testing is available

Answer

Apixaban use makes the patient ineligible for thrombectomy

Answer

Apixaban must be reversed with vitamin K before thrombolysis can be considered

Answer

Apixaban is protective against ischaemic stroke so this is likely a haemorrhagic event

Answer

Apixaban has no relevance to acute stroke management decisions

uk-dipimc MCQ (SBA): Stroke and DOAC Therapy

A 72-year-old female with known atrial fibrillation on apixaban 5 mg BD presents with sudden-onset right-sided hemiplegia and global aphasia. Symptom onset was 90 minutes ago. Her blood glucose is 5.8 mmol/L. What is the significance of her apixaban use in the context of acute stroke management?