A 70-year-old vegan woman presents with paraesthesia and gait disturbance. FBC shows macrocytic anaemia, and B12 levels are very low. Intrinsic factor...

Question

A 70-year-old vegan woman presents with paraesthesia and gait disturbance. FBC shows macrocytic anaemia, and B12 levels are very low. Intrinsic factor antibodies are positive. What is the most appropriate long-term management?

Accepted Answer

IM hydroxocobalamin course then 3-monthly injections lifelong

Answer

Oral cyanocobalamin tablets lifelong

Answer

Single IM hydroxocobalamin injection only

Answer

Folate supplementation alone

Answer

Dietary modification only

uk-plab-1 MCQ (SBA): Pernicious anaemia

A 70-year-old vegan woman presents with paraesthesia and gait disturbance. FBC shows macrocytic anaemia, and B12 levels are very low. Intrinsic factor antibodies are positive. What is the most appropriate long-term management?