Question

A 72-year-old man with long-standing osteoarthritis of the knees takes regular high-dose Ibuprofen and presents with ankle swelling, rising creatinine, and blood pressure 168/100 mmHg. What is the most appropriate first step in managing his deteriorating renal function?

Accepted Answer

Stop NSAIDs and review renal function, considering alternative analgesia

Answer

Increase Ibuprofen dose to improve mobility

Answer

Continue NSAIDs and add an ACE inhibitor

Answer

Start a thiazide diuretic and continue all other medications

Answer

Reassure that this is expected with ageing and do nothing

Practice question

A 72-year-old man with long-standing osteoarthritis of the knees takes regular high-dose Ibuprofen and presents with ankle swelling, rising creatinine, and blood pressure 168/100 mmHg. What is the most appropriate first step in managing his deteriorating renal function?