A 69-year-old man is admitted with sepsis due to pneumonia. His creatinine has risen from a baseline of 90 micromol per litre to 230 micromol per litr...

Question

A 69-year-old man is admitted with sepsis due to pneumonia. His creatinine has risen from a baseline of 90 micromol per litre to 230 micromol per litre over 48 hours. He is on Ramipril and Ibuprofen. Urine output is reduced. What is the most appropriate immediate management regarding his medications?

Accepted Answer

Stop Ramipril and NSAIDs and optimise fluid status

Answer

Increase Ramipril dose to improve renal perfusion

Answer

Continue all regular medications unchanged

Answer

Start high-dose loop diuretics to force diuresis

Answer

Start long-term dialysis immediately

uk-plab-1 MCQ (SBA): Acute kidney injury