A 68-year-old man with chronic kidney disease stage 3 is admitted with sepsis and becomes oliguric. Serum creatinine has risen from 120 to 210 micromo...

Question

A 68-year-old man with chronic kidney disease stage 3 is admitted with sepsis and becomes oliguric. Serum creatinine has risen from 120 to 210 micromol/L in 24 hours. According to NICE AKI guidance, what is the most important immediate management step?

Accepted Answer

Stop nephrotoxic drugs, optimise volume status with a fluid challenge and monitor urine output closely.

Answer

Start high-dose loop diuretics to force diuresis.

Answer

Arrange immediate dialysis for all rises in creatinine.

Answer

Restrict all fluid intake until creatinine normalises.

Answer

Start ACE inhibitor to improve renal perfusion.

uk-plab-1 MCQ (SBA): Acute kidney injury in sepsis

A 68-year-old man with chronic kidney disease stage 3 is admitted with sepsis and becomes oliguric. Serum creatinine has risen from 120 to 210 micromol/L in 24 hours. According to NICE AKI guidance, what is the most important immediate management step?