A 34-year-old woman suddenly develops generalised urticaria, wheeze, hoarse voice and hypotension 10 minutes after receiving intravenous Co-amoxiclav ...

Question

A 34-year-old woman suddenly develops generalised urticaria, wheeze, hoarse voice and hypotension 10 minutes after receiving intravenous Co-amoxiclav in the day unit. She weighs 70 kg. What is the most appropriate first-line drug treatment?

Accepted Answer

Adrenaline 0.5 mg of 1:1000 intramuscularly in the anterolateral thigh.

Answer

Chlorphenamine 10 mg IV.

Answer

Hydrocortisone 200 mg IV.

Answer

Adrenaline 1 mg of 1:10,000 intravenously as a rapid bolus.

Answer

Salbutamol 5 mg via nebuliser driven by air only.

uk-plab-1 MCQ (SBA): Anaphylaxis – initial management

A 34-year-old woman suddenly develops generalised urticaria, wheeze, hoarse voice and hypotension 10 minutes after receiving intravenous Co-amoxiclav in the day unit. She weighs 70 kg. What is the most appropriate first-line drug treatment?