A 49-year-old woman presents with fatigue, weight gain, cold intolerance and constipation. Examination reveals dry skin and periorbital puffiness. TSH is elevated and free T4 is low. What is the most appropriate initial treatment in primary care?AStart Levothyroxine and titrate according to TSHBStart Carbimazole and beta-blockerCArrange urgent radioactive iodine therapyDReassure that no treatment is requiredEStart high-dose PrednisoloneCheck my answer