A 65-year-old man with chronic kidney disease (eGFR 45 mL/min/1.73 m²) has an albumin:creatinine ratio of 45 mg/mmol. He is not diabetic and his blood...

Question

A 65-year-old man with chronic kidney disease (eGFR 45 mL/min/1.73 m²) has an albumin:creatinine ratio of 45 mg/mmol. He is not diabetic and his blood pressure is 148/90 mmHg. What is the most appropriate management regarding renin–angiotensin system blockade?

Accepted Answer

Start an ACE inhibitor such as Ramipril and titrate to blood pressure and albuminuria targets

Answer

Do not use ACE inhibitors in CKD

Answer

Use a beta-blocker as first-line for renal protection

Answer

Start Allopurinol

Answer

No pharmacological treatment is needed

uk-plab-1 MCQ (SBA): Chronic kidney disease with albuminuria

A 65-year-old man with chronic kidney disease (eGFR 45 mL/min/1.73 m²) has an albumin:creatinine ratio of 45 mg/mmol. He is not diabetic and his blood pressure is 148/90 mmHg. What is the most appropriate management regarding renin–angiotensin system blockade?