ModerateRespiratoryAcute exacerbation of COPDuk-plab-1
A 68-year-old man with known chronic obstructive pulmonary disease (COPD) presents with increased breathlessness, sputum volume and purulence. His oxygen saturation is 88% on air and arterial blood gases show pH 7.34, PaCO₂ 7.0 kPa, PaO₂ 7.2 kPa. What is the most appropriate initial management in the emergency department?