A 64-year-old man with metastatic colorectal cancer has severe constant pain despite regular Paracetamol. He is opioid-naive. What is the most appropr...

Question

A 64-year-old man with metastatic colorectal cancer has severe constant pain despite regular Paracetamol. He is opioid-naive. What is the most appropriate next-step analgesia in line with UK palliative care guidance?

Accepted Answer

Start regular oral Morphine modified-release with immediate-release Morphine for breakthrough pain

Answer

Start Fentanyl transdermal patch as first-line

Answer

Give PRN Tramadol only

Answer

Use NSAIDs alone at maximised doses

Answer

Start strong opioids only once he is bedbound

uk-plab-1 MCQ (SBA): Cancer pain management with opioids

A 64-year-old man with metastatic colorectal cancer has severe constant pain despite regular Paracetamol. He is opioid-naive. What is the most appropriate next-step analgesia in line with UK palliative care guidance?